Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28266404 | 0.78 | PARP1 (0.44) | PARP1LMNAALDH1A1GAAMAPT | |
| SCHEMBL19104416 | 0.76 | PARP1 (0.39) | PARP1LMNAALDH1A1GAAMAPT | |
| SCHEMBL17601073 | 0.76 | HTT (0.38) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL25435536 | 0.74 | MAPK8 (0.36) | ALDH1A1MAPTMERTKRAB9AKCNH2 | |
| SCHEMBL12636463 | 0.72 | PARP1 (0.47) | PARP1LMNAALDH1A1GAAMAPT | |
| SCHEMBL18166826 | 0.72 | SRPK1 (0.39) | PARP1LMNAALDH1A1GAAMAPT | |
| SCHEMBL1130670 | 0.71 | PARP1 (0.43) | PARP1LMNAALDH1A1GAAMAPT | |
| SCHEMBL1881628 | 0.71 | PARP1 (0.43) | PARP1LMNAALDH1A1GAAMAPT | |
| SCHEMBL12886408 | 0.71 | LMNA (0.43) | PARP1LMNAALDH1A1GAAMAPT | |
| SCHEMBL1725109 | 0.71 | PARP1 (0.43) | PARP1LMNAALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867348-B | Imidazopyrimidines as IL-17 modulators | 詹森药业有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-115867348-A | Imidazopyrimidines as IL-17 modulators | 詹森药业有限公司 | 2023-03-28 | — | — | CN | disclosed |