Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 4/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33377163 | 0.88 | PRKDC (0.56) | LGMNMAPTNPC1TP53ALOX15 | |
| SCHEMBL30210309 | 0.86 | IP6K1 (0.63) | MAPTALOX15CCNCCDK8IP6K1 | |
| SCHEMBL30210340 | 0.85 | MAP4K4 (0.64) | MAPTNPC1TP53ALOX15RAB9A | |
| SCHEMBL23999520 | 0.82 | MAPKAPK2 (0.54) | MAPTNPC1TP53ALOX15RAB9A | |
| SCHEMBL24010995 | 0.82 | CCNC (0.54) | LGMNMAPTNPC1TP53ALOX15 | |
| SCHEMBL24005893 | 0.80 | CCNC (0.55) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL30811429 | 0.80 | LRRK2 (0.51) | MAPTNPC1RAB9ASMN1; SMN2MAPKAPK2 | |
| SCHEMBL23999924 | 0.79 | MAPKAPK2 (0.57) | MAPTNPC1RAB9ASMN1; SMN2MAPKAPK2 | |
| SCHEMBL24532295 | 0.78 | MEN1 (0.55) | MAPTNPC1RAB9ASMN1; SMN2MAPKAPK2 | |
| SCHEMBL29681119 | 0.78 | MEN1 (0.55) | MAPTNPC1RAB9ASMN1; SMN2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024404-A | Benzopyridine derivatives and uses thereof | 四川汇宇制药股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-115996939-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |