Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.64 |
| ▸ | IP6K1 | Q92551 | 4/20 | 0.61 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | S100B | P04271 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30210309 | 0.98 | IP6K1 (0.63) | MAP4K4IP6K1IP6K3MEN1GAA | |
| SCHEMBL30210341 | 0.85 | LGMN (0.53) | MAP4K4IP6K1MEN1KMT2AALDH1A1 | |
| SCHEMBL23999937 | 0.81 | MAP4K4 (0.56) | MAP4K4IP6K1IP6K3MEN1GAA | |
| SCHEMBL26326746 | 0.81 | MAP4K4 (0.56) | MAP4K4IP6K1IP6K3MEN1GAA | |
| SCHEMBL24003940 | 0.81 | MAP4K4 (0.56) | MAP4K4IP6K1IP6K3MEN1GAA | |
| SCHEMBL23999855 | 0.79 | IP6K1 (0.55) | MAP4K4IP6K1IP6K3MEN1GAA | |
| SCHEMBL24010819 | 0.79 | IP6K1 (0.55) | MAP4K4IP6K1IP6K3MEN1GAA | |
| SCHEMBL25831270 | 0.79 | ALDH1A1 (0.55) | MAP4K4IP6K1IP6K3MEN1GAA | |
| SCHEMBL5137752 | 0.78 | MAP4K4 (1.00) | MAP4K4IP6K1IP6K3MEN1GAA | |
| SCHEMBL24010989 | 0.78 | MAP4K4 (0.52) | MAP4K4IP6K1IP6K3MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996939-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |