Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930466 | 1.00 | MAPT (0.38) | MAPTPTPN1MEN1KMT2ANPC1 | |
| SCHEMBL23930475 | 0.86 | NPC1 (0.38) | MAPTPTPN1MEN1KMT2ANPC1 | |
| SCHEMBL30210882 | 0.86 | NPC1 (0.38) | MAPTPTPN1MEN1KMT2ANPC1 | |
| SCHEMBL23930626 | 0.86 | MEN1 (0.44) | MAPTPTPN1MEN1KMT2ACDK5 | |
| SCHEMBL23930490 | 0.86 | MEN1 (0.44) | MAPTPTPN1MEN1KMT2ACDK5 | |
| SCHEMBL23930461 | 0.86 | MEN1 (0.44) | MAPTPTPN1MEN1KMT2ACDK5 | |
| SCHEMBL30210845 | 0.86 | CDK5 (0.39) | MAPTPTPN1MEN1KMT2ANPC1 | |
| SCHEMBL23930581 | 0.86 | CDK5 (0.39) | MAPTPTPN1MEN1KMT2ANPC1 | |
| SCHEMBL23930641 | 0.85 | CDK5 (0.41) | MAPTMEN1KMT2ACDK5CDK5R1 | |
| SCHEMBL30210764 | 0.85 | CDK5 (0.41) | MAPTMEN1KMT2ACDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139287-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-4139287-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2023-03-01 | — | — | EP | claimed |
| EP-4139287-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2023-03-01 | — | — | EP | disclosed |