Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.49 |
| ▸ | CCR1 | P32246 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812145 | 1.00 | CCR3 (0.49) | CCR3CCR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1812149 | 1.00 | CCR3 (0.49) | CCR3CCR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1814456 | 0.94 | CCR3 (0.48) | CCR3CCR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1814452 | 0.94 | CCR3 (0.48) | CCR3CCR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1812419 | 0.90 | CCR3 (0.44) | CCR3CCR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1812420 | 0.90 | CCR3 (0.44) | CCR3CCR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1812124 | 0.84 | CCR3 (0.69) | CCR3CCR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1812120 | 0.84 | CCR3 (0.69) | CCR3CCR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1814223 | 0.84 | CCR3 (0.43) | CCR3CCR1ALDH1A1MEN1KMT2A | |
| SCHEMBL13828234 | 0.84 | ALDH1A1 (0.36) | CCR3CCR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4164643-A1 | METHODS OF IMPROVING RETINA-ASSOCIATED DISEASE OUTCOME USING CCR3-INHIBITORS | Alkahest, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |
| CN-115697334-A | Methods of improving retinal related disease outcomes using CCR3 inhibitors | 万能溶剂有限公司 | 2023-02-03 | — | — | CN | disclosed |