Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 12/20 | 0.43 |
| ▸ | HTR2C | P28335 | 12/20 | 0.43 |
| ▸ | HTR2A | P28223 | 11/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787143 | 0.85 | MAOA (0.42) | PARP1CRBN | |
| SCHEMBL1500226 | 0.85 | MAOA (0.42) | PARP1CRBN | |
| SCHEMBL30040395 | 0.85 | PARP1 (0.49) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30763946 | 0.85 | CRBN (0.53) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL25235039 | 0.84 | HTR2B (0.49) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30132224 | 0.84 | HTR2B (0.49) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL26963072 | 0.84 | PARP1 (0.45) | PARP1HTR2BHTR2CHTR2APARP10 | |
| SCHEMBL5946759 | 0.84 | POLB (0.43) | PARP1CRBN | |
| SCHEMBL23880784 | 0.84 | PARP1 (0.48) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL1500062 | 0.82 | MAOA (0.46) | MAPK1PARP10PARP11CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |