Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.34 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | RAD52 | P43351 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28336494 | 0.98 | KCNH2 (0.44) | KCNH2SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL30330147 | 0.93 | KCNH2 (0.41) | KCNH2SMN1; SMN2NPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL29251700 | 0.93 | SMN1; SMN2 (0.44) | KCNH2SMN1; SMN2NPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL30212766 | 0.91 | SMN1; SMN2 (0.50) | KCNH2SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL5284691 | 0.91 | KCNH2 (0.55) | KCNH2SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL5304040 | 0.91 | KCNH2 (0.55) | KCNH2SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL28139801 | 0.91 | NPC1 (0.45) | KCNH2SMN1; SMN2NPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL30212678 | 0.89 | SMN1; SMN2 (0.53) | KCNH2SMN1; SMN2NPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL30212928 | 0.89 | SMN1; SMN2 (0.53) | KCNH2SMN1; SMN2NPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL30212734 | 0.89 | SMN1; SMN2 (0.53) | KCNH2SMN1; SMN2NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046704-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2023-03-30 | — | — | WO | disclosed |
| EP-4155723-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2023-03-29 | — | — | EP | disclosed |