Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31419764 | 0.90 | NQO1 (0.85) | NQO1MAPTKMT2AKDM4ERAB9A | |
| SCHEMBL10362376 | 0.90 | NQO1 (0.85) | NQO1MAPTKMT2AKDM4ERAB9A | |
| SCHEMBL10362375 | 0.90 | NQO1 (0.85) | NQO1MAPTKMT2AKDM4ERAB9A | |
| SCHEMBL13403222 | 0.89 | NQO1 (0.63) | NQO1MAPTKMT2AKDM4ERAB9A | |
| SCHEMBL28125674 | 0.89 | NQO1 (0.63) | NQO1MAPTKMT2AKDM4ERAB9A | |
| SCHEMBL7757059 | 0.82 | NQO1 (1.00) | NQO1MAPTKMT2AKDM4ERAB9A | |
| SCHEMBL7757057 | 0.82 | NQO1 (1.00) | NQO1MAPTKMT2AKDM4ERAB9A | |
| SCHEMBL13100090 | 0.80 | NQO1 (0.81) | NQO1MAPTKMT2AKDM4ERAB9A | |
| SCHEMBL30214941 | 0.80 | NQO1 (0.72) | NQO1MAPTKMT2AKDM4ERAB9A | |
| SCHEMBL5820556 | 0.75 | NQO1 (0.72) | NQO1MAPTKMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023027654-A1 | CARBOXYLIC ACID HYDRAZIDE-COUMARINE HYBRID COMPOUNDS ANTIINFLAMMATORY AND ANTICONVULSANE AGENT | CUKUROVA UNIVERSITESI REKTORLUGU (TR) | 2023-03-02 | — | — | WO | claimed |