⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217276 | 0.88 | — | — | |
| SCHEMBL29237241 | 0.88 | — | — | |
| SCHEMBL30217140 | 0.87 | FFAR1 (0.35) | — | |
| SCHEMBL29237233 | 0.87 | FFAR1 (0.35) | — | |
| SCHEMBL29336940 | 0.80 | BRD4 (0.32) | — | |
| SCHEMBL30285454 | 0.80 | BRD4 (0.32) | — | |
| SCHEMBL29237262 | 0.78 | FFAR1 (0.36) | — | |
| SCHEMBL30217019 | 0.78 | FFAR1 (0.36) | — | |
| SCHEMBL30217087 | 0.76 | — | — | |
| SCHEMBL29237831 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396179-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034992-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |