Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29336940 | 1.00 | BRD4 (0.32) | BRD4GCKPTGS2 | |
| SCHEMBL29336583 | 0.90 | BACE1 (0.37) | BRD4GCKPTGS2 | |
| SCHEMBL30285449 | 0.90 | BACE1 (0.37) | BRD4GCKPTGS2 | |
| SCHEMBL29336943 | 0.88 | DRD1 (0.32) | — | |
| SCHEMBL30285675 | 0.86 | — | — | |
| SCHEMBL29336939 | 0.86 | — | — | |
| SCHEMBL30285506 | 0.81 | BACE1 (0.36) | BRD4 | |
| SCHEMBL29336584 | 0.81 | BACE1 (0.36) | BRD4 | |
| SCHEMBL30217137 | 0.80 | — | — | |
| SCHEMBL30217167 | 0.80 | DRD1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396176-A1 | INDOLE COMPOUNDS AND USES THEREOF IN THE TREATEMENT OF CYSTIC FIBROSIS | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034946-A1 | INDOLE COMPOUNDS AND USES THEREOF IN THE TREATEMENT OF CYSTIC FIBROSIS | GENZYME CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |