SCHEMBL30217224

SCHEMBL30217224

COC(=O)CCc1cccc(C(c2cnc(-c3cc(Oc4c(F)cc5[nH]ccc5c4F)ccc3F)[nH]2)C(C)(C)C)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29237349 1.00 FFAR1 (0.32) FFAR1
SCHEMBL30217229 0.93 FFAR1 (0.37) FFAR1
SCHEMBL29237541 0.93 FFAR1 (0.37) FFAR1
SCHEMBL30217219 0.85 FFAR1 (0.32) FFAR1
SCHEMBL29237809 0.85 FFAR1 (0.32) FFAR1
SCHEMBL30217005 0.85 PTGS1 (0.33) —
SCHEMBL30217199 0.83 CDK8 (0.33) —
SCHEMBL30217248 0.83 FFAR1 (0.31) FFAR1
SCHEMBL30967895 0.83 FFAR1 (0.33) FFAR1
SCHEMBL29237854 0.83 FFAR1 (0.33) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396179-A1 INDOLE COMPOUNDS AND METHODS OF USE GENZYME CORPORATION (US) 2024-07-10 — — EP disclosed
WO-2023034992-A1 INDOLE COMPOUNDS AND METHODS OF USE GENZYME CORPORATION (US) 2023-03-09 — — WO disclosed
Send feedback