Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237541 | 0.87 | FFAR1 (0.37) | — | |
| SCHEMBL30217229 | 0.87 | FFAR1 (0.37) | — | |
| SCHEMBL30217224 | 0.85 | FFAR1 (0.32) | — | |
| SCHEMBL29237349 | 0.85 | FFAR1 (0.32) | — | |
| SCHEMBL30217245 | 0.79 | PTGS1 (0.33) | PTGS1AKR1C3AKR1C2APPCYP2C19 | |
| SCHEMBL31108496 | 0.77 | PTGER1 (0.32) | — | |
| SCHEMBL29237247 | 0.77 | THRA (0.32) | — | |
| SCHEMBL30217196 | 0.77 | THRA (0.32) | — | |
| SCHEMBL29336943 | 0.75 | DRD1 (0.32) | — | |
| SCHEMBL30217334 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396179-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023034992-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |