Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.56 |
| ▸ | F2 | P00734 | 5/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237722 | 1.00 | F10 (0.56) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL29237386 | 0.88 | TNKS (0.48) | F10F2RHEB | |
| SCHEMBL30967906 | 0.88 | TNKS (0.48) | F10F2RHEB | |
| SCHEMBL29336701 | 0.85 | F10 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL29237351 | 0.84 | F10 (0.46) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL30938228 | 0.84 | F10 (0.46) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL30967798 | 0.82 | SNCA (0.43) | RHEB | |
| SCHEMBL29237678 | 0.82 | SNCA (0.43) | RHEB | |
| SCHEMBL30967836 | 0.82 | F10 (0.44) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL27276128 | 0.82 | F10 (0.44) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396179-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023034992-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |