Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | RHEB | Q15382 | 2/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237386 | 1.00 | TNKS (0.48) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL30217325 | 0.88 | F10 (0.56) | F10RHEBF2 | |
| SCHEMBL29237722 | 0.88 | F10 (0.56) | F10RHEBF2 | |
| SCHEMBL30967798 | 0.87 | SNCA (0.43) | BRD4RHEBPPARD | |
| SCHEMBL29237678 | 0.87 | SNCA (0.43) | BRD4RHEBPPARD | |
| SCHEMBL31108617 | 0.87 | L3MBTL1 (0.44) | RHEBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29337702 | 0.79 | USP2 (0.43) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL31108471 | 0.78 | RHEB (0.48) | RHEBPPARDPRKCQPRKCD | |
| SCHEMBL27275531 | 0.78 | RHEB (0.48) | RHEBPPARDPRKCQPRKCD | |
| SCHEMBL30967840 | 0.78 | PRKCQ (0.47) | BRD4RHEBPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |