Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM6A | O15550 | 1/20 | 0.43 |
| ▸ | TET3 | O43151 | 1/20 | 0.43 |
| ▸ | KDM4B | O94953 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25097311 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1KDM4AEGLN1 | |
| SCHEMBL28512682 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1L3MBTL1KDM4AEGLN1 | |
| SCHEMBL1126280 | 0.78 | KMT2A (0.62) | KDM4EALDH1A1L3MBTL1KDM4AEGLN1 | |
| SCHEMBL6962756 | 0.78 | KDM4E (0.68) | KDM4EALDH1A1L3MBTL1KDM4AEGLN1 | |
| SCHEMBL31082793 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1KMT2ATDP1MAPT | |
| SCHEMBL1126077 | 0.78 | MAPK1 (0.44) | KDM4EALDH1A1L3MBTL1TP53KMT2A | |
| SCHEMBL30439125 | 0.78 | MAPK1 (0.44) | KDM4EALDH1A1L3MBTL1TP53KMT2A | |
| SCHEMBL30530504 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1L3MBTL1KDM4AEGLN1 | |
| SCHEMBL24317845 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1L3MBTL1KDM4AEGLN1 | |
| SCHEMBL3500515 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1L3MBTL1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395891-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| EP-4110464-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-01-04 | — | — | EP | disclosed |