SCHEMBL3500515

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23357760	0.89	CYP1A2 (0.48)	KDM4EKMT2AMEN1METAP2CYP1A2
	SCHEMBL3498758	0.80	ALDH1A1 (0.39)	KDM4EMAPTMAPK1KMT2AMEN1
	SCHEMBL3500609	0.80	CCKBR (0.38)	KDM4EMAPTMAPK1KMT2AMEN1
	SCHEMBL246997	0.80	MAPT (0.44)	KDM4EMAPTMAPK1KMT2AMEN1
	Bicarbonate SCHEMBL30641166	0.79	MAPT (0.41)	KDM4EMAPTMAPK1KMT2AMEN1
	SCHEMBL17413609	0.78	MEN1 (0.50)	KDM4EMAPTMAPK1KMT2AMEN1
	SCHEMBL30217795	0.76	KDM4E (0.46)	KDM4EMAPTKMT2ACYP1A2L3MBTL1
	SCHEMBL25097311	0.76	KDM4E (0.46)	KDM4EMAPTKMT2ACYP1A2L3MBTL1
	SCHEMBL19034443	0.76	GABRP (0.41)	KDM4EMAPTKMT2AMEN1CYP1A2
	SCHEMBL3501568	0.74	L3MBTL1 (0.44)	KDM4EMAPTMAPK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.