Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504102 | 0.82 | NPSR1 (0.50) | NPSR1FLT3DYRK1AMIFADORA3 | |
| SCHEMBL30359488 | 0.77 | NPSR1 (0.39) | NPSR1FLT3CHEK1MAP4K4CSF1R | |
| SCHEMBL21623709 | 0.65 | PRMT5 (0.32) | GAA | |
| SCHEMBL18324191 | 0.65 | CDK8 (0.53) | NPSR1FLT3CHEK1MAP4K4CSF1R | |
| SCHEMBL380169 | 0.65 | KDR (0.35) | FLT3KDRPKMKDM4EALDH1A1 | |
| SCHEMBL10138747 | 0.65 | KDM4E (0.51) | FLT3PKMKDM4EALDH1A1GLA | |
| SCHEMBL557273 | 0.65 | KDR (0.41) | FLT3CSF1RKDRDYRK1ADYRK1B | |
| SCHEMBL21591164 | 0.65 | FLT3 (0.40) | FLT3KDRPKMKDM4EALDH1A1 | |
| SCHEMBL10174940 | 0.65 | KDR (0.47) | FLT3KDR | |
| SCHEMBL3325146 | 0.63 | POLB (0.51) | FLT3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025244-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND APPLICATION THEREOF | 科辉智药生物科技(深圳)有限公司 | 2023-03-02 | — | — | WO | disclosed |