Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84864 | 0.82 | NPSR1 (0.50) | NPSR1TGFBR1FLT3DYRK1ACHEK1 | |
| SCHEMBL30218031 | 0.77 | NPSR1 (0.39) | NPSR1FLT3CDK8ROCK1DYRK1A | |
| Dimethylamine SCHEMBL7859896 | 0.77 | NPSR1 (0.46) | NPSR1TGFBR1FLT3DYRK1ANPC1 | |
| SCHEMBL17102638 | 0.68 | NPC1 (0.41) | NPSR1FLT3CDK8ROCK1DYRK1A | |
| SCHEMBL7922826 | 0.68 | KDM4E (0.54) | FLT3NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10238918 | 0.65 | CYP1A2 (0.56) | TGFBR1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL260258 | 0.65 | CDK8 (0.56) | CDK8ROCK1DYRK1ACHEK1MAP4K4 | |
| SCHEMBL3151800 | 0.65 | BRAF (0.37) | HPGDALDH1A1TP53MAPTPKM | |
| SCHEMBL15233358 | 0.65 | ADORA3 (0.52) | NPSR1FLT3CDK8ROCK1DYRK1A | |
| SCHEMBL20049424 | 0.65 | KDM4E (0.41) | FLT3KDRNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747255-A1 | MODULATORS OF THE ADENOSINE A2A AND A2B RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025018901-A1 | MODULATORS OF THE ADENOSINE A2A AND A2B RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2025-01-23 | — | — | WO | disclosed |
| EP-4433485-A1 | ADENOSINE RECEPTOR ANTAGONISTS | Crossignal Therapeutics, Inc. (US) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |