Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOL1 | O14791 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24098954 | 1.00 | APOL1 (0.56) | APOL1 | |
| SCHEMBL24099512 | 1.00 | APOL1 (0.56) | APOL1 | |
| SCHEMBL24099167 | 0.92 | APOL1 (0.66) | APOL1 | |
| SCHEMBL30218335 | 0.92 | APOL1 (0.66) | APOL1 | |
| SCHEMBL24099508 | 0.83 | APOL1 (0.54) | APOL1 | |
| SCHEMBL22118330 | 0.81 | APOL1 (0.85) | APOL1 | |
| SCHEMBL24098926 | 0.79 | APOL1 (0.41) | APOL1 | |
| SCHEMBL30184356 | 0.79 | APOL1 (0.41) | APOL1 | |
| SCHEMBL24099510 | 0.78 | APOL1 (0.51) | APOL1 | |
| SCHEMBL24098932 | 0.78 | APOL1 (0.51) | APOL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165023-A1 | INHIBITORS OF APOL1 AND USE OF THE SAME | Vertex Pharmaceuticals Incorporated (US) | 2023-04-19 | — | — | EP | disclosed |
| CN-115867532-A | Inhibitors of APOL1 and uses thereof | 弗特克斯药品有限公司 | 2023-03-28 | — | — | CN | disclosed |