Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 11/20 | 0.61 |
| ▸ | AKT2 | P31751 | 9/20 | 0.41 |
| ▸ | AKT1 | P31749 | 8/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19048703 | 0.78 | USP7 (0.76) | USP7AKT2AKT1 | |
| SCHEMBL361569 | 0.71 | AKT2 (0.78) | AKT2AKT1 | |
| SCHEMBL1658724 | 0.71 | RAB9A (0.47) | — | |
| SCHEMBL11028623 | 0.68 | USP7 (0.69) | USP7AKT2AKT1 | |
| SCHEMBL1659968 | 0.68 | CGAS (0.47) | — | |
| SCHEMBL7467961 | 0.67 | AKT1 (0.56) | USP7AKT2AKT1 | |
| SCHEMBL1318629 | 0.67 | AKT1 (0.53) | USP7AKT2AKT1 | |
| SCHEMBL13325800 | 0.66 | AKT2 (0.60) | AKT2AKT1 | |
| SCHEMBL7683359 | 0.65 | CDK2 (0.59) | USP7AKT2AKT1 | |
| SCHEMBL11026812 | 0.65 | USP7 (0.60) | USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117751117-A | SARM1 enzyme activity inhibitor and application thereof | 科辉智药生物科技（无锡）有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-115724839-A | SARM1 enzyme activity inhibitor and application thereof | 科辉智药生物科技(深圳)有限公司 | 2023-03-03 | — | — | CN | disclosed |