SCHEMBL30218650

SCHEMBL30218650

CC(C)(C)c1cc(Br)cc(Br)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
CYP3A4 P08684 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
CA2 P00918 4/20 0.50
CA1 P00915 2/20 0.50
IGF1R P08069 1/20 0.50
CISD1 Q9NZ45 1/20 0.50
GABRA1 P14867 1/20 0.50
GABRB1 P18505 1/20 0.50
GABRA2 P47869 1/20 0.50
GABRB2 P47870 1/20 0.50
SMN1; SMN2 Q16637 5/20 0.48
ALDH1A1 P00352 4/20 0.48
POLB P06746 1/20 0.48
TYR P14679 1/20 0.48
ALOX15 P16050 4/20 0.46
ALOX12 P18054 2/20 0.46
HIF1A Q16665 2/20 0.46
HPGD P15428 1/20 0.46
CASP1 P29466 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1530860 1.00 TSHR (0.56) TSHRCYP3A4TDP1CA2CA1
SCHEMBL49614 0.88 CA2 (0.64) TSHRCYP3A4TDP1CA2CA1
SCHEMBL7191865 0.86 CYP3A4 (0.56) TSHRCYP3A4TDP1CA2CA1
SCHEMBL1764729 0.85 CYP3A4 (0.50) TSHRCYP3A4TDP1CA2CA1
SCHEMBL28572779 0.84 CA2 (0.58) TSHRCYP3A4TDP1CA2CA1
Methylamine SCHEMBL3205669 0.84 CA2 (0.58) TSHRCYP3A4TDP1CA2CA1
SCHEMBL5597001 0.83 TSHR (0.52) TSHRCYP3A4TDP1CA2CA1
SCHEMBL3073021 0.80 TSHR (0.56) TSHRCYP3A4TDP1CA2CA1
SCHEMBL1628174 0.80 SMN1; SMN2 (0.71) TSHRCYP3A4TDP1CA2CA1
SCHEMBL15563525 0.80 CYP2C9 (0.63) TSHRCA2CA1GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283507-A Preparation method of 2-substituted-4, 6-dibromophenol 山东京博石油化工有限公司 2023-06-23 CN disclosed
CN-115724721-A Preparation method of 2-substituent-4-bromophenol 山东京博石油化工有限公司 2023-03-03 CN disclosed