Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.58 |
| ▸ | MGAM | O43451 | 10/20 | 0.58 |
| ▸ | AMY1A | P0DUB6 | 10/20 | 0.58 |
| ▸ | SI | P14410 | 10/20 | 0.58 |
| ▸ | MGAM2 | Q2M2H8 | 10/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 2/20 | 0.58 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.58 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13134139 | 1.00 | GAA (0.58) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL535388 | 0.87 | KMT2A (0.59) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL23780256 | 0.84 | KMT2A (0.62) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL13604208 | 0.83 | GAA (0.58) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL535030 | 0.83 | ASAH1 (0.64) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL2494210 | 0.83 | MGAM (0.58) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL21821605 | 0.83 | MGAM (0.58) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL14300892 | 0.82 | GAA (0.54) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL17814919 | 0.82 | KMT2A (0.60) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL534899 | 0.82 | ASAH1 (0.66) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996924-B | Substituted pyrazolyl compounds and methods of use thereof | 诺华医药股份公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-115996924-A | Substituted pyrazolyl compounds and methods of use thereof | 奇努克医疗加拿大公司 | 2023-04-21 | — | — | CN | disclosed |
| EP-4153585-A1 | SUBSTITUTED PYRAZOLYL COMPOUNDS AND METHODS OF USE THEREOF | Chinook Therapeutics Canada, Inc. (CA) | 2023-03-29 | — | — | EP | disclosed |