Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30219805 | 1.00 | CYP2D6 (0.50) | CYP2D6SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL30219798 | 0.95 | POLB (0.49) | CYP2D6SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL4788580 | 0.90 | CYP2D6 (0.61) | CYP2D6MEN1KMT2ALMNACYP2C9 | |
| SCHEMBL30219806 | 0.84 | CYP2C9 (0.62) | CYP2D6POLBMEN1KMT2ALMNA | |
| SCHEMBL30219836 | 0.84 | CYP2D6 (0.50) | CYP2D6SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL30219822 | 0.84 | CYP2D6 (0.50) | CYP2D6SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL30219800 | 0.84 | CYP2C9 (0.62) | CYP2D6POLBMEN1KMT2ALMNA | |
| SCHEMBL30219801 | 0.83 | L3MBTL1 (0.55) | CYP2D6SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL30219799 | 0.83 | L3MBTL1 (0.55) | CYP2D6SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11436603 | 0.82 | CYP2D6 (0.74) | CYP2D6SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444005-B | Method for synthesizing novel glutaric acid compound from diaryl substituted non-activated olefin | 四川大学 | 2023-03-03 | — | — | CN | disclosed |