Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15478440 | 1.00 | DRD1 (0.35) | DRD1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1111225 | 1.00 | DRD1 (0.35) | DRD1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1111229 | 1.00 | DRD1 (0.35) | DRD1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29528319 | 1.00 | DRD1 (0.35) | DRD1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14498419 | 0.91 | SMN1; SMN2 (0.32) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL14498430 | 0.90 | NPC1 (0.32) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL14498409 | 0.90 | DRD1 (0.33) | DRD1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23119029 | 0.88 | P2RY1 (0.31) | MAPTNPC1RAB9ASMN1; SMN2P2RY1 | |
| SCHEMBL14523590 | 0.88 | P2RY1 (0.31) | MAPTNPC1RAB9ASMN1; SMN2P2RY1 | |
| SCHEMBL14498394 | 0.87 | DRD1 (0.33) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677580-B | Quaternary-carbon-containing indandione tetrahydroquinoline spiro alkaloid, preparation method thereof and application thereof in preparation of antitumor drugs | 中南民族大学 | 2025-02-07 | — | — | CN | claimed |
| CN-115677580-A | Tetrahydroquinoline spiro alkaloid containing quaternary carbon indandione, preparation method thereof and application thereof in preparing antitumor drugs | 中南民族大学 | 2023-02-03 | — | — | CN | claimed |
| CN-115677580-A | Tetrahydroquinoline spiro alkaloid containing quaternary carbon indandione, preparation method thereof and application thereof in preparing antitumor drugs | 中南民族大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-115677580-A | Tetrahydroquinoline spiro alkaloid containing quaternary carbon indandione, preparation method thereof and application thereof in preparing antitumor drugs | 中南民族大学 | 2023-02-03 | — | — | CN | disclosed |