Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15478440 | 1.00 | DRD1 (0.35) | DRD1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30220116 | 1.00 | DRD1 (0.35) | DRD1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1111225 | 1.00 | DRD1 (0.35) | DRD1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29528319 | 1.00 | DRD1 (0.35) | DRD1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14498419 | 0.91 | SMN1; SMN2 (0.32) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL14498430 | 0.90 | NPC1 (0.32) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL14498409 | 0.90 | DRD1 (0.33) | DRD1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23119029 | 0.88 | P2RY1 (0.31) | MAPTNPC1RAB9ASMN1; SMN2P2RY1 | |
| SCHEMBL14523590 | 0.88 | P2RY1 (0.31) | MAPTNPC1RAB9ASMN1; SMN2P2RY1 | |
| SCHEMBL14498394 | 0.87 | DRD1 (0.33) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651863-B | Unsaturated thioglycoside compound and selective synthesis method and application thereof | 华东师范大学 | 2023-11-10 | — | — | CN | claimed |
| CN-115677580-A | Tetrahydroquinoline spiro alkaloid containing quaternary carbon indandione, preparation method thereof and application thereof in preparing antitumor drugs | 中南民族大学 | 2023-02-03 | — | — | CN | claimed |
| CN-109721508-B | Method for preparing 3-pentenenitrile | 安徽省安庆市曙光化工股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-113651863-A | Unsaturated thioglycoside compound and selective synthesis method and application thereof | 华东师范大学 | 2021-11-16 | — | — | CN | claimed |
| CN-109721508-A | A method of preparing 3 pentene nitrile | 安徽省安庆市曙光化工股份有限公司 | 2019-05-07 | — | — | CN | claimed |
| CN-109651195-A | The method of 2- allyl acetonitrile isomerization reaction generation 3 pentene nitrile | 安徽省安庆市曙光化工股份有限公司 | 2019-04-19 | — | — | CN | claimed |
| EP-2443128-B1 | New synthetic route for the preparation of alpha-amino boronic esters | LEK PHARMACEUTICALS (SI) | 2017-12-20 | — | — | EP | claimed |
| EP-2443129-B1 | PROCESS FOR HYDROGENATION OF HALOGENOALKENES WITHOUT DEHALOGENATION | LEK PHARMACEUTICALS (SI) | 2016-11-23 | — | — | EP | claimed |
| US-9315525-B2 | Synthetic route for the preparation of α-amino boronic acid derivatives via substituted alk-1-ynes | LEK PHARMACEUTICALS D.D. (SI) | 2016-04-19 | — | — | US | claimed |
| US-8785674-B2 | Process for hydrogenation of halogenoalkenes without dehalogenation | LEK PHARMACEUTICALS D.D. (SL) | 2014-07-22 | — | — | US | claimed |
| US-20120231993-A1 | NEW SYNTHETIC ROUTE FOR THE PREPARATION OF ALPHA-AMINO BORONIC ACID DERIVATIVES via SUBSTITUTED ALK-1-YNES | LEK PHARMACEUTICALS D.D. (SI) | 2012-09-13 | — | — | US | claimed |
| US-20120220794-A1 | PROCESS FOR HYDROGENATION OF HALOGENOALKENES WITHOUT DEHALOGENATION | LEK PHARMACEUTICALS D.D. (SI) | 2012-08-30 | — | — | US | claimed |
| EP-2443128-A2 | New synthetic route for the preparation of alpha-amino boronic esters | LEK Pharmaceuticals d.d. (SI) | 2012-04-25 | — | — | EP | claimed |
| EP-2443129-A2 | PROCESS FOR HYDROGENATION OF HALOGENOALKENES WITHOUT DEHALOGENATION | LEK Pharmaceuticals d.d. (SI) | 2012-04-25 | — | — | EP | claimed |
| EP-2280016-A1 | New synthetic route for the preparation of alpha-amino boronic esters via substituted alk-1-ynes | LEK Pharmaceuticals d.d. (SI) | 2011-02-02 | — | — | EP | claimed |
| WO-2010146176-A2 | PROCESS FOR HYDROGENATION OF HALOGENOALKENES WITHOUT DEHALOGENATION | LEK PHARMACEUTICALS D.D. (SI) | 2010-12-23 | — | — | WO | claimed |
| WO-2010146172-A2 | NEW SYNTHETIC ROUTE FOR THE PREPARATION OF α-AMINO BORONIC ACID DERIVATIVES VIA SUBSTITUTED ALK-1-YNES | LEK PHARMACEUTICALS D.D. (SI) | 2010-12-23 | — | — | WO | claimed |
| CN-116444400-A | Chiral alpha- (trichloromethyl) amine compound and preparation method thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | disclosed |
| US-20060084820-A1 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-04-20 | — | — | US | disclosed |
| US-6551467-B1 | Microwave heated very rapid highly selective (chemo-, regio-and stereo-) allylic substitutions utilising molybdenum or palladium together with an auxiliary ligand as catalytic system | PERSONAL CHEMISTRY I UPPSALA AB (SE) | 2003-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084820-A1 | Enantioselective, catalytic allylation of ketones and olefins | AKR1C2, TECR, AKR1C4 | DRD1 2207/4885MAPT 2756/4885NPC1 1539/4885 |
| US-20120220794-A1 | PROCESS FOR HYDROGENATION OF HALOGENOALKENES WITHOUT DEHALOGENATION | HDHD5, DEK, HCK | DRD1 557/4885MAPT 3500/4885NPC1 3437/4885 |
| US-20120231993-A1 | NEW SYNTHETIC ROUTE FOR THE PREPARATION OF ALPHA-AMINO BORONIC ACID DERIVATIVES via SUBSTITUTED ALK-1-YNES | ALK, ABL2, ALKBH3 | DRD1 559/4885MAPT 2338/4885NPC1 2759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.