Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 17/20 | 0.70 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.60 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.60 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.60 |
| ▸ | RAF1 | P04049 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | GCGR | P47871 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30220453 | 1.00 | TEK (0.70) | TEKMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL17835458 | 1.00 | TEK (0.70) | TEKMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL17847351 | 0.96 | TEK (0.64) | TEKMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4552055 | 0.90 | MAPK14 (0.76) | TEKMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6926311 | 0.88 | TEK (0.65) | TEKMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30553015 | 0.83 | TEK (1.00) | TEKMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6447875 | 0.80 | MAPK13 (0.72) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL23887914 | 0.80 | TEK (0.79) | TEKMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL155371 | 0.80 | ALOX5 (0.62) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL15606600 | 0.80 | MAPK14 (0.71) | MAPK13MAPK12MAPK11MAPK14RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126047-A1 | METHODS FOR TREATING ALZHEIMER'S DISEASE | Jefferies, Wilfred (CA) | 2023-02-08 | — | — | EP | disclosed |