Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | BMP4 | P12644 | 2/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HCK | P08631 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23993543 | 1.00 | ACP1 (0.38) | ACP1SYKMTORP2RX3BMP4 | |
| SCHEMBL30224304 | 0.94 | ACP1 (0.36) | ACP1SYKMTORP2RX3BMP4 | |
| SCHEMBL30224464 | 0.89 | SYK (0.36) | ACP1SYKMTORQPCTQPCTL | |
| SCHEMBL23994016 | 0.89 | SYK (0.36) | ACP1SYKMTORQPCTQPCTL | |
| SCHEMBL23993918 | 0.87 | SYK (0.38) | ACP1SYKMTORQPCTQPCTL | |
| SCHEMBL23994827 | 0.85 | SYK (0.41) | ACP1SYKMTORQPCTQPCTL | |
| SCHEMBL25005777 | 0.85 | SYK (0.41) | ACP1SYKMTORQPCTQPCTL | |
| SCHEMBL23994182 | 0.85 | SYK (0.37) | ACP1SYKMTORQPCTQPCTL | |
| SCHEMBL23993986 | 0.85 | SYK (0.37) | ACP1SYKMTORQPCTQPCTL | |
| SCHEMBL30224492 | 0.85 | SYK (0.37) | ACP1SYKMTORQPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143194-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-03-08 | — | — | EP | disclosed |