Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.40 |
| ▸ | NCF1 | P14598 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 3/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29185299 | 1.00 | NPY5R (0.40) | NPY5RNCF1TUBB4ATUBBTUBA3C | |
| SCHEMBL30224798 | 0.94 | NPY5R (0.45) | NPY5RNCF1TUBB4ATUBBTUBA3C | |
| SCHEMBL30224822 | 0.94 | NPY5R (0.41) | NPY5RNCF1TUBB4ATUBBTUBA3C | |
| SCHEMBL29185291 | 0.94 | NPY5R (0.45) | NPY5RNCF1TUBB4ATUBBTUBA3C | |
| SCHEMBL30183196 | 0.92 | NCF1 (0.41) | NPY5RNCF1TUBB4ATUBBTUBA3C | |
| SCHEMBL29205617 | 0.92 | NCF1 (0.41) | NPY5RNCF1TUBB4ATUBBTUBA3C | |
| SCHEMBL24988646 | 0.92 | NPY5R (0.44) | NPY5RNCF1TUBB4ATUBBTUBA3C | |
| SCHEMBL29185262 | 0.91 | NPY5R (0.37) | NPY5RNCF1TUBB4ATUBBTUBA3C | |
| SCHEMBL30224927 | 0.91 | NPY5R (0.37) | NPY5RNCF1TUBB4ATUBBTUBA3C | |
| SCHEMBL29185270 | 0.90 | NPY5R (0.44) | NPY5RTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |