Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 3/20 | 0.33 |
| ▸ | CDC7 | O00311 | 5/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 2/20 | 0.32 |
| ▸ | CLK2 | P49760 | 2/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29185259 | 1.00 | ADORA2A (0.33) | ADORA2AADORA1KITCDC7GSK3B | |
| SCHEMBL29185312 | 0.92 | KIT (0.41) | KITCDC7CLK1CLK2CLK3 | |
| SCHEMBL30224789 | 0.92 | KIT (0.41) | KITCDC7CLK1CLK2CLK3 | |
| SCHEMBL30224960 | 0.84 | ALDH1A1 (0.33) | CD38 | |
| SCHEMBL29185285 | 0.84 | ALDH1A1 (0.33) | CD38 | |
| SCHEMBL30182945 | 0.82 | PDE1A (0.38) | KITCDC7GSK3BCLK1CLK2 | |
| SCHEMBL27237593 | 0.79 | ADORA2A (0.37) | ADORA2AADORA1KITCDC7CD38 | |
| SCHEMBL30224754 | 0.79 | ADORA2A (0.37) | ADORA2AADORA1KITCDC7CD38 | |
| SCHEMBL30224886 | 0.78 | ADORA2A (0.39) | ADORA2AADORA1CDC7CD38DBF4 | |
| SCHEMBL29185265 | 0.78 | ADORA2A (0.37) | ADORA2AADORA1KITCDC7CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |