Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 2/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27237596 | 1.00 | CSF1R (0.43) | CSF1RKCNH3RIPK2BRD4NPY5R | |
| SCHEMBL30224905 | 0.93 | TACR1 (0.35) | CSF1RNPY5RACHEBACE1KIT | |
| SCHEMBL29185260 | 0.93 | TACR1 (0.35) | CSF1RNPY5RACHEBACE1KIT | |
| SCHEMBL29185274 | 0.92 | NPY5R (0.34) | CSF1RNPY5RACHEBACE1KIT | |
| SCHEMBL30224931 | 0.92 | NPY5R (0.34) | CSF1RNPY5RACHEBACE1KIT | |
| SCHEMBL30182999 | 0.92 | CSF1R (0.47) | CSF1RKCNH3RIPK2BRD4NPY5R | |
| SCHEMBL30183019 | 0.90 | CSF1R (0.46) | CSF1RKCNH3RIPK2BRD4NPY5R | |
| SCHEMBL29205587 | 0.90 | CSF1R (0.46) | CSF1RKCNH3RIPK2BRD4NPY5R | |
| SCHEMBL30224759 | 0.87 | CSF1R (0.40) | CSF1RBRD4NPY5RKITFLT3 | |
| SCHEMBL30224873 | 0.86 | CSF1R (0.40) | CSF1RBRD4NPY5RKITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |