SCHEMBL30183019 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	CSF1R	P07333	6/20	0.46

▸	KCNH3	Q9ULD8	1/20	0.40

▸	NPY5R	Q15761	4/20	0.38

▸	RIPK2	O43353	1/20	0.38

▸	BRD4	O60885	1/20	0.35

▸	SSTR3	P32745	1/20	0.34

▸	HIF1A	Q16665	1/20	0.34

▸	CCNK	O75909	1/20	0.34

▸	CDK9	P50750	1/20	0.34

▸	PDE5A	O76074	1/20	0.33

▸	CRHR1	P34998	1/20	0.33

▸	PRMT5	O14744	1/20	0.33

▸	CREBBP	Q92793	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29205587	1.00	CSF1R (0.46)	CSF1RKCNH3NPY5RRIPK2BRD4
SCHEMBL30182999	0.90	CSF1R (0.47)	CSF1RKCNH3NPY5RRIPK2BRD4
SCHEMBL30224925	0.90	CSF1R (0.43)	CSF1RKCNH3NPY5RRIPK2BRD4
SCHEMBL27237596	0.90	CSF1R (0.43)	CSF1RKCNH3NPY5RRIPK2BRD4
SCHEMBL30182940	0.86	CSF1R (0.42)	CSF1RNPY5RBRD4
SCHEMBL27237598	0.85	CSF1R (0.43)	CSF1RKCNH3NPY5RRIPK2BRD4
SCHEMBL3416697	0.83	CSF1R (0.51)	CSF1RKCNH3NPY5RRIPK2SSTR3
SCHEMBL29185260	0.82	TACR1 (0.35)	CSF1RNPY5R
SCHEMBL30224905	0.82	TACR1 (0.35)	CSF1RNPY5R
SCHEMBL31022339	0.82	CSF1R (0.40)	CSF1RNPY5RBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023013996-A1	INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF	주식회사 미토이뮨테라퓨틱스	2023-02-09	—	—	WO	disclosed