Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 7/20 | 0.39 |
| ▸ | PDE1A | P54750 | 4/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30224759 | 0.94 | CSF1R (0.40) | PDE1BPDE1AKITFLT3CSF1R | |
| SCHEMBL27237572 | 0.94 | CSF1R (0.40) | PDE1BPDE1AKITFLT3CSF1R | |
| SCHEMBL30224873 | 0.94 | CSF1R (0.40) | PDE1BPDE1AKITFLT3CSF1R | |
| SCHEMBL27237575 | 0.93 | TUBB4A (0.34) | PDE1BPDE1AKITFLT3CSF1R | |
| SCHEMBL30224954 | 0.93 | TUBB4A (0.34) | PDE1BPDE1AKITFLT3CSF1R | |
| SCHEMBL24988874 | 0.90 | CSF1R (0.40) | PDE1BPDE1AKITFLT3CSF1R | |
| SCHEMBL30224124 | 0.90 | CSF1R (0.40) | PDE1BPDE1AKITFLT3CSF1R | |
| SCHEMBL30848980 | 0.89 | NPY5R (0.34) | PDE1BPDE1AKITFLT3CSF1R | |
| SCHEMBL29185295 | 0.89 | NPY5R (0.34) | PDE1BPDE1AKITFLT3CSF1R | |
| SCHEMBL29185302 | 0.88 | ADORA2A (0.35) | KITCSF1RADORA2AADORA1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |