Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29185271 | 1.00 | FBP1 (0.38) | FBP1XDHCYP19A1GRIN2DGRIN3B | |
| SCHEMBL29185306 | 0.94 | FBP1 (0.39) | FBP1XDHCYP19A1F2RL3PLCG2 | |
| SCHEMBL30224930 | 0.94 | FBP1 (0.39) | FBP1XDHCYP19A1F2RL3PLCG2 | |
| SCHEMBL29185287 | 0.91 | FBP1 (0.39) | FBP1XDHCYP19A1GRIN2DGRIN3B | |
| SCHEMBL30848959 | 0.91 | FBP1 (0.39) | FBP1XDHCYP19A1GRIN2DGRIN3B | |
| SCHEMBL30224943 | 0.90 | F2RL3 (0.40) | FBP1XDHCYP19A1F2RL3PLCG2 | |
| SCHEMBL29205659 | 0.89 | CYP19A1 (0.41) | FBP1XDHCYP19A1PLCG2NPY5R | |
| SCHEMBL31022529 | 0.89 | FBP1 (0.38) | FBP1XDHCYP19A1GRIN2DGRIN3B | |
| SCHEMBL30848953 | 0.89 | F2RL3 (0.41) | FBP1XDHCYP19A1F2RL3PLCG2 | |
| SCHEMBL27237592 | 0.89 | F2RL3 (0.41) | FBP1XDHCYP19A1F2RL3PLCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |