SCHEMBL30225642

SCHEMBL30225642

N[C@@H](CCSC[C@H]1O[C@@H](n2cnc3c(NCCc4ccc(-c5ccccc5)cc4)ncnc32)[C@H](O)[C@@H]1O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DNMT3B Q9UBC3 9/20 1.00
▸ DNMT1 P26358 8/20 1.00
▸ DOT1L Q8TEK3 11/20 0.78
▸ PRMT1 Q99873 1/20 0.70
▸ CARM1 Q86X55 1/20 0.65
▸ EHMT2 Q96KQ7 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17309766 1.00 DNMT3B (1.00) DNMT3BDNMT1DOT1LPRMT1CARM1
SCHEMBL14174643 0.96 DNMT3B (1.00) DNMT3BDNMT1DOT1LPRMT1CARM1
SCHEMBL30225688 0.96 DNMT3B (1.00) DNMT3BDNMT1DOT1LPRMT1CARM1
SCHEMBL5055207 0.96 DNMT3B (1.00) DNMT3BDNMT1DOT1LPRMT1CARM1
SCHEMBL17309760 0.96 DNMT3B (1.00) DNMT3BDNMT1DOT1LPRMT1CARM1
SCHEMBL17309762 0.91 DNMT3B (1.00) DNMT3BDNMT1DOT1LPRMT1CARM1
SCHEMBL14174713 0.91 DNMT3B (1.00) DNMT3BDNMT1DOT1LPRMT1CARM1
SCHEMBL5052474 0.89 DNMT3B (1.00) DNMT3BDNMT1DOT1LPRMT1
SCHEMBL17309755 0.89 DNMT3B (1.00) DNMT3BDNMT1DOT1LPRMT1
SCHEMBL30225680 0.89 DNMT3B (1.00) DNMT3BDNMT1DOT1LPRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952182-B1 Compounds and methods for increasing the immune response to papillomavirus UNIV HEIDELBERG (DE) 2022-11-23 — — EP claimed
US-20250161351-A1 CANCER TREATMENT BY ARSENIC TRIOXIDE COMBINATION THERAPY Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2025-05-22 — — US disclosed
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