SCHEMBL30226752

SCHEMBL30226752

C=C(C)C(=O)Oc1c(OC)cc(OC(C)=O)c2cc(Cl)ccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 1/20 0.57
AMY1A P0DUB6 1/20 0.41
TNFSF11 O14788 1/20 0.40
HTT P42858 2/20 0.39
NQO1 P15559 1/20 0.39
TSHR P16473 1/20 0.37
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TUBB4A P04350 3/20 0.36
TUBB P07437 3/20 0.36
TUBA3C P0DPH7 3/20 0.36
TUBA1B P68363 3/20 0.36
TUBA4A P68366 3/20 0.36
TUBB4B P68371 3/20 0.36
TUBB3 Q13509 3/20 0.36
TUBB2A Q13885 3/20 0.36
TUBB8 Q3ZCM7 3/20 0.36
TUBA3E Q6PEY2 3/20 0.36
TUBA1A Q71U36 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30226877 0.93 ABCB11 (0.54) ABCB11AMY1ALMNAMAPTSMN1; SMN2
SCHEMBL9629306 0.91 ABCB11 (0.68) ABCB11AMY1ATNFSF11HTTNQO1
SCHEMBL9627379 0.88 ABCB11 (0.68) ABCB11AMY1ATNFSF11HTTNQO1
SCHEMBL30226817 0.87 HTT (0.42) ABCB11TNFSF11HTTNQO1TSHR
SCHEMBL30226933 0.87 ABCB11 (0.52) ABCB11AMY1AHTTTSHRLMNA
SCHEMBL9628189 0.86 ABCB11 (0.70) ABCB11AMY1ATNFSF11HTTLMNA
SCHEMBL30226609 0.86 ABCB11 (0.51) ABCB11HTTLMNAMAPTTUBB4A
SCHEMBL9627417 0.85 ABCB11 (0.68) ABCB11AMY1ATNFSF11HTTNQO1
SCHEMBL30226827 0.84 ABCB11 (0.45) ABCB11HTTLMNATUBB4ATUBB
SCHEMBL30226744 0.84 ABCB11 (0.52) ABCB11AMY1ALMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023013209-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION CONTAINING 4-SUBSTITUTED OXY-1-(METH)ACRYLOYLOXYNAPHTHALENE COMPOUND, AND SECONDARY BATTERY COMPRISING SAME エア・ウォーター・パフォーマンスケミカル株式会社 2023-02-09 WO disclosed