Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.63 |
| ▸ | HCAR3 | P49019 | 15/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26049179 | 1.00 | HDAC3 (0.63) | HDAC3HDAC1HDAC2HCAR3HCAR2 | |
| SCHEMBL24086714 | 0.88 | HDAC1 (0.61) | HDAC3HDAC1HDAC2 | |
| SCHEMBL30227186 | 0.85 | HDAC3 (0.62) | HDAC3HDAC1HDAC2MAOB | |
| SCHEMBL23992274 | 0.85 | HDAC3 (0.62) | HDAC3HDAC1HDAC2MAOB | |
| SCHEMBL24086713 | 0.82 | HDAC1 (0.55) | HDAC3HDAC1HDAC2 | |
| SCHEMBL25693478 | 0.81 | HDAC1 (0.54) | HDAC3HDAC1HDAC2 | |
| SCHEMBL23992185 | 0.78 | HDAC3 (1.00) | HDAC3HDAC1HDAC2 | |
| SCHEMBL30227167 | 0.78 | HDAC3 (1.00) | HDAC3HDAC1HDAC2 | |
| SCHEMBL24086703 | 0.76 | HDAC3 (0.69) | HDAC3HDAC1HDAC2MAOB | |
| SCHEMBL12074867 | 0.74 | PAM (0.55) | HDAC3HDAC1HDAC2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116033904-A | Histone deacetylase inhibitor for tumor microenvironment immunomodulation | 华上生技医药股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| EP-4142733-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2023-03-08 | — | — | EP | disclosed |