Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.62 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186096 | 1.00 | CCR5 (0.62) | CCR5CXCR4CYP2C9 | |
| Hydrochloric Acid SCHEMBL5578984 | 0.99 | CCR5 (0.63) | CCR5CXCR4CYP2C9 | |
| Hydrochloric Acid SCHEMBL5578982 | 0.99 | CCR5 (0.63) | CCR5CXCR4CYP2C9 | |
| SCHEMBL6186509 | 0.92 | CCR5 (0.63) | CCR5CXCR4CYP2C9 | |
| SCHEMBL6187084 | 0.92 | CCR5 (0.63) | CCR5CXCR4CYP2C9 | |
| SCHEMBL30227476 | 0.92 | CCR5 (0.63) | CCR5CXCR4CYP2C9 | |
| SCHEMBL30227269 | 0.92 | CCR5 (0.63) | CCR5CXCR4CYP2C9 | |
| SCHEMBL6186062 | 0.92 | CCR5 (0.67) | CCR5CXCR4CYP2C9 | |
| SCHEMBL30227457 | 0.92 | CCR5 (0.67) | CCR5CXCR4CYP2C9 | |
| Hydrochloric Acid SCHEMBL5578811 | 0.92 | CCR5 (0.64) | CCR5CXCR4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143235-A1 | METHODS AND COMPOSITIONS FOR TREATING CYTOKINE STORM INFECTIONS, INCLUDING COVID-19, BY INHIBITING CCR5/CCL5 INTERACTION | IncellDx, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |