Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.53 |
| ▸ | JAK3 | P52333 | 19/20 | 0.53 |
| ▸ | JAK2 | O60674 | 16/20 | 0.53 |
| ▸ | JAK1 | P23458 | 16/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22054128 | 1.00 | TYK2 (0.53) | TYK2JAK3JAK2JAK1GPR119 | |
| SCHEMBL23878910 | 0.89 | TYK2 (0.57) | TYK2JAK3JAK2JAK1P2RX3 | |
| SCHEMBL22054065 | 0.88 | AURKA (0.53) | TYK2JAK3JAK2JAK1GPR119 | |
| SCHEMBL30147209 | 0.88 | AURKA (0.53) | TYK2JAK3JAK2JAK1GPR119 | |
| SCHEMBL22055250 | 0.85 | TYK2 (0.55) | TYK2JAK3JAK2JAK1GPR119 | |
| SCHEMBL23878957 | 0.85 | TYK2 (0.55) | TYK2JAK3JAK2JAK1GPR119 | |
| SCHEMBL23878810 | 0.85 | GPR119 (0.50) | TYK2JAK3JAK2JAK1GPR119 | |
| SCHEMBL23889558 | 0.85 | GPR119 (0.50) | TYK2JAK3JAK2JAK1GPR119 | |
| SCHEMBL22054196 | 0.85 | GPR119 (0.50) | TYK2JAK3JAK2JAK1GPR119 | |
| SCHEMBL23878809 | 0.84 | GPR119 (0.47) | TYK2JAK3JAK2JAK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003441-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-115925705-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-116003441-A | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115925705-A | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-111511738-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-01-20 | — | — | CN | disclosed |