Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228331 | 0.90 | MEN1 (0.43) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL30228195 | 0.85 | MEN1 (0.42) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL30228256 | 0.84 | MEN1 (0.49) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL30227899 | 0.84 | MEN1 (0.42) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL30228000 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL30228094 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL25278269 | 0.80 | GRM2 (0.39) | MEN1KMT2AMAPTKDM4ECA12 | |
| SCHEMBL30228136 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL30228104 | 0.79 | MEN1 (0.40) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL30227938 | 0.78 | IGLV6-57 (0.51) | ALDH1A1MEN1KMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |