Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228294 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAL3MBTL1RAB9ATDP1 | |
| SCHEMBL31711135 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAL3MBTL1RAB9ATDP1 | |
| SCHEMBL31710449 | 0.89 | ALDH1A1 (0.48) | ALDH1A1LMNAL3MBTL1RAB9ATDP1 | |
| SCHEMBL30228074 | 0.89 | ALDH1A1 (0.48) | ALDH1A1LMNAL3MBTL1RAB9ATDP1 | |
| SCHEMBL30228276 | 0.89 | ALDH1A1 (0.48) | ALDH1A1LMNAL3MBTL1RAB9ATDP1 | |
| SCHEMBL30228340 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNAL3MBTL1RAB9ATDP1 | |
| SCHEMBL30228217 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNAL3MBTL1RAB9ATDP1 | |
| SCHEMBL30228426 | 0.84 | ALDH1A1 (0.52) | ALDH1A1LMNAL3MBTL1RAB9ATDP1 | |
| SCHEMBL30228444 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNAL3MBTL1RAB9ATDP1 | |
| SCHEMBL30228413 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNAL3MBTL1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |