Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 8/20 | 0.56 |
| ▸ | CA9 | Q16790 | 8/20 | 0.56 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228248 | 0.87 | CA12 (0.70) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL22431749 | 0.87 | CA12 (0.70) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL30228211 | 0.76 | CA12 (0.67) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL29036860 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Hymecromone SCHEMBL29624431 | 0.73 | HSD17B3 (1.00) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Hymecromone SCHEMBL29364837 | 0.73 | HSD17B3 (1.00) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Hymecromone SCHEMBL2357040 | 0.73 | HSD17B3 (1.00) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Hymecromone SCHEMBL24150 | 0.73 | HSD17B3 (1.00) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL28585333 | 0.73 | CA12 (0.74) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL14424515 | 0.72 | CA12 (0.75) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |