Hymecromone

Hymecromone

SCHEMBL24150

Cc1cc(=O)oc2cc(O)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 8/20 1.00
ALDH1A1 P00352 7/20 1.00
KDM4E B2RXH2 6/20 1.00
CA12 O43570 6/20 1.00
CA9 Q16790 6/20 1.00
HPGD P15428 4/20 1.00
HSD17B10 Q99714 4/20 1.00
GAA P10253 4/20 1.00
GLA P06280 3/20 1.00
AKR1B1 P15121 3/20 1.00
MAOB P27338 3/20 1.00
CASP1 P29466 2/20 1.00
CASP7 P55210 2/20 1.00
MCL1 Q07820 2/20 1.00
LMNA P02545 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP2C9 P11712 1/20 1.00
UGT1A1 P22309 1/20 1.00
KDR P35968 1/20 1.00
DYRK1A Q13627 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hymecromone SCHEMBL29364837 1.00 HSD17B3 (1.00) HSD17B3ALDH1A1KDM4ECA12CA9
Hymecromone SCHEMBL29624431 1.00 HSD17B3 (1.00) HSD17B3ALDH1A1KDM4ECA12CA9
Hymecromone SCHEMBL2357040 1.00 HSD17B3 (1.00) HSD17B3ALDH1A1KDM4ECA12CA9
Hymecromone SCHEMBL31014 0.98 HSD17B3 (0.96) HSD17B3ALDH1A1KDM4ECA12CA9
Hymecromone SCHEMBL27924142 0.98 HSD17B3 (0.96) HSD17B3ALDH1A1KDM4ECA12CA9
Hymecromone SCHEMBL27728511 0.96 HSD17B3 (0.93) HSD17B3ALDH1A1KDM4ECA12CA9
Hymecromone SCHEMBL2256610 0.95 ALDH1A1 (0.90) HSD17B3ALDH1A1KDM4ECA12CA9
Hymecromone SCHEMBL28882003 0.93 KDM4E (0.87) HSD17B3ALDH1A1KDM4ECA12CA9
Hymecromone SCHEMBL3272842 0.93 HSD17B3 (0.87) HSD17B3ALDH1A1KDM4ECA12CA9
Hymecromone SCHEMBL7594956 0.93 KDM4E (0.87) HSD17B3ALDH1A1KDM4ECA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 19482 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079945-A Coumarin derivative containing substituted phenyl ether structure, preparation method and application thereof 2026-05-26 CN claimed
US-12638448-B2 Compositions, methods, and kits for detection of lipolytic activity LONZA LTD (CH) 2026-05-26 US claimed
US-12631648-B2 Compounds for the detection of homocysteine and its method of preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2026-05-19 US claimed
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
CN-121203077-B Stimulus-responsive hydrogel for repairing tissue injury and preparation method thereof 浙江中医药大学 2026-05-19 CN claimed
CN-122060838-A In-situ screening and identifying method for high-activity rice bran endogenous lipase and application thereof 河南工业大学 2026-05-19 CN claimed
US-12618095-B2 Medium for Bacillus cereus group detection SHIMADZU DIAGNOSTICS CORPORATION (JP) 2026-05-05 US claimed
US-20260096569-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES APEEL TECH INC (US) 2026-04-09 US claimed
CN-118925816-B Method for carrying out water quality detection by embedding coliform group with alginate hydrogel 祥符实验室 2026-02-27 CN claimed
WO-2025262251-A1 BIOMASS DETERMINATION BASED ON ACTIVITIY OF ENZYMES WITH DIFFERENT PH OPTIMA BACTIQUANT A/S (DK) 2025-12-26 WO claimed
US-4358569-A FLAME RESISTANT THERMOPLASTIC MOLDING MATERIAL OF GOOD IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1982-11-09 US claimed
WO-1982002601-A1 SOLID PHASE SYSTEM FOR LIGAND ASSAY AMERICAN HOSPITAL SUPPLY CORP (US) 1982-08-05 WO claimed
WO-1982002401-A1 BLENDS OF COPOLYESTER-CARBONATE WITH POLYSULFONE GEN ELECTRIC (US) 1982-07-22 WO claimed
US-4308348-A SALMONELLA, SERRATIA, PROTEUS, PROVIDENCIA LABORATOIRE DE RECHERCHE API (FR) 1981-12-29 US claimed
US-4278508-A Method of detecting a cathodic corrosion site on a metallized substrate RCA CORPORATION (US) 1981-07-14 US claimed
EP-0022768-A1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS. SYVA CO (US) 1981-01-28 EP claimed
US-4241047-A HYMECROMONE AND CHENODEOXYCHOLIC ACID LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1980-12-23 US claimed
EP-0022768-A4 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS. SYVA CO (US) 1980-08-18 EP claimed
WO-1979000882-A1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS SYVA CO (US) 1979-11-01 WO claimed
US-4102747-A CLEAVAGE OF CHROMOGENIC SUBSTANCES, MEDICAL DIAGNOSIS AMERICAN HOSPITAL SUPPLY CORPORATION (US) 1978-07-25 US claimed