Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228349 | 0.82 | KMT2A (0.57) | ALBMAOBCA12CA9CA1 | |
| SCHEMBL30228021 | 0.82 | ALB (0.48) | ALBMAOBCA12CA9CA1 | |
| SCHEMBL30228165 | 0.82 | ALB (0.48) | ALBMAOBCA12CA9CA1 | |
| SCHEMBL30228464 | 0.81 | MAOB (0.62) | ALBMAOBCA12CA9KCNA3 | |
| SCHEMBL30228287 | 0.80 | IGLV6-57 (0.46) | CA12CA9KCNA3ALDH1A1LMNA | |
| SCHEMBL30228242 | 0.78 | ALB (0.47) | ALBMAOBCA12CA9CA1 | |
| SCHEMBL30227897 | 0.78 | ALB (0.48) | ALBMAOBCA12CA9CA1 | |
| SCHEMBL30228107 | 0.77 | ALB (0.47) | ALBMAOBCA12CA9CA1 | |
| SCHEMBL30228271 | 0.77 | ALB (0.47) | ALBMAOBCA12CA9KCNA3 | |
| SCHEMBL30228128 | 0.76 | CA12 (0.54) | ALBMAOBCA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |