Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228021 | 0.84 | ALB (0.48) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL30228271 | 0.83 | ALB (0.47) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL30228107 | 0.83 | ALB (0.47) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL30228464 | 0.83 | MAOB (0.62) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL30228234 | 0.82 | ALB (0.47) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL30227897 | 0.82 | ALB (0.48) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL30228165 | 0.82 | ALB (0.48) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL30228128 | 0.79 | CA12 (0.54) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL30228242 | 0.78 | ALB (0.47) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL30228426 | 0.78 | ALDH1A1 (0.52) | KMT2AALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |