Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | IGLV6-57 | P01721 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228113 | 0.87 | IGLV6-57 (0.45) | CA12CA9IGLV6-57ALDH1A1KDM4E | |
| SCHEMBL30228469 | 0.84 | IGLV6-57 (0.43) | CA12CA9IGLV6-57ALDH1A1KDM4E | |
| SCHEMBL30228399 | 0.84 | IGLV6-57 (0.43) | IGLV6-57ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL30228027 | 0.83 | IGLV6-57 (0.40) | CA12CA9IGLV6-57ALDH1A1KDM4E | |
| SCHEMBL31719974 | 0.81 | PTGER3 (0.32) | KMT2ALMNASMN1; SMN2 | |
| SCHEMBL30228420 | 0.81 | KCNA3 (0.41) | CA12CA9IGLV6-57ALDH1A1KDM4E | |
| SCHEMBL30228135 | 0.79 | IGLV6-57 (0.44) | CA12CA9IGLV6-57ALDH1A1KDM4E | |
| SCHEMBL30228277 | 0.78 | IGLV6-57 (0.38) | CA12CA9IGLV6-57ALDH1A1KDM4E | |
| SCHEMBL30228253 | 0.77 | IGLV6-57 (0.43) | IGLV6-57ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL30228072 | 0.76 | IGLV6-57 (0.42) | CA12CA9IGLV6-57ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |