Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGLV6-57 | P01721 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228469 | 0.93 | IGLV6-57 (0.43) | IGLV6-57ALDH1A1GLACYP3A4HPGD | |
| SCHEMBL30228113 | 0.88 | IGLV6-57 (0.45) | IGLV6-57ALDH1A1GLACYP3A4HPGD | |
| SCHEMBL30228247 | 0.84 | CA12 (0.41) | IGLV6-57ALDH1A1GLACYP3A4HPGD | |
| SCHEMBL30228027 | 0.83 | IGLV6-57 (0.40) | IGLV6-57ALDH1A1GLACYP3A4HPGD | |
| SCHEMBL30228420 | 0.81 | KCNA3 (0.41) | IGLV6-57ALDH1A1GLACYP3A4HPGD | |
| SCHEMBL30228135 | 0.79 | IGLV6-57 (0.44) | IGLV6-57ALDH1A1GLACYP3A4HPGD | |
| SCHEMBL30228277 | 0.79 | IGLV6-57 (0.38) | IGLV6-57ALDH1A1GLACYP3A4HPGD | |
| SCHEMBL30228253 | 0.78 | IGLV6-57 (0.43) | IGLV6-57ALDH1A1GLACYP3A4HPGD | |
| SCHEMBL30228423 | 0.76 | IGLV6-57 (0.45) | IGLV6-57ALDH1A1GLACYP3A4HPGD | |
| SCHEMBL30228289 | 0.75 | IGLV6-57 (0.48) | IGLV6-57ALDH1A1GLACYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |