Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LATS1 | O95835 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228367 | 1.00 | ACACB (0.41) | ACACBACACAKDM4ENPC1RAB9A | |
| SCHEMBL28992119 | 0.92 | MIF (0.42) | ACACBACACAKDM4ENPC1RAB9A | |
| SCHEMBL30228810 | 0.87 | MIF (0.41) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL21864837 | 0.83 | KDM4E (0.42) | KDM4ENPC1RAB9AMAPTNCF1 | |
| SCHEMBL28992114 | 0.83 | ALDH1A1 (0.47) | KDM4ENPC1RAB9AMAPT | |
| SCHEMBL30228559 | 0.83 | ALDH1A1 (0.47) | KDM4ENPC1RAB9AMAPT | |
| SCHEMBL30228856 | 0.83 | ALDH1A1 (0.47) | KDM4ENPC1RAB9AMAPT | |
| SCHEMBL28992126 | 0.83 | ALDH1A1 (0.47) | KDM4ENPC1RAB9AMAPT | |
| SCHEMBL21865489 | 0.83 | KDM4E (0.43) | KDM4ENPC1RAB9AMAPTNCF1 | |
| SCHEMBL21864962 | 0.83 | KDM4E (0.41) | KDM4ENPC1RAB9AMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988106-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2023-03-31 | — | — | CN | disclosed |