SCHEMBL30229028

SCHEMBL30229028

CC(C)(C)OC(=O)N(C1CC1)[C@H]1CCN(c2ccc(Cl)nn2)C1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
MEN1 O00255 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
LMNA P02545 2/20 0.47
HTT P42858 1/20 0.47
CHRNB2 P17787 3/20 0.42
CHRNA4 P43681 3/20 0.42
CHRNB4 P30926 2/20 0.42
CHRNA3 P32297 2/20 0.42
AAK1 Q2M2I8 1/20 0.40
PANK3 Q9H999 2/20 0.40
PDE10A Q9Y233 1/20 0.40
GPR119 Q8TDV5 2/20 0.39
TRPV1 Q8NER1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25105323 1.00 KMT2A (0.49) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL30228730 1.00 KMT2A (0.49) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL25105974 1.00 KMT2A (0.49) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL30228895 0.97 KMT2A (0.48) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL25104855 0.97 KMT2A (0.48) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL30229011 0.97 KMT2A (0.48) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL25105544 0.97 KMT2A (0.48) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL25106016 0.97 KMT2A (0.48) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL30228932 0.97 KMT2A (0.48) KMT2AMEN1SMN1; SMN2LMNAHTT
SCHEMBL25105512 0.95 KMT2A (0.47) KMT2AMEN1SMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333397-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC (US) 2025-10-30 US disclosed
WO-2023034836-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. (US) 2023-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333397-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING RBM17, SNRPA, SNRPA1 KMT2A 3214/4885MEN1 3822/4885SMN1; SMN2 301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.