Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | PLAT | P00750 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16402566 | 0.75 | PARP1 (0.38) | PARP1CDC7ALOX5ALOX5APFEN1 | |
| SCHEMBL16682624 | 0.75 | CDC7 (0.36) | PARP1PLATCDC7ALOX5ALOX5AP | |
| SCHEMBL18209656 | 0.75 | CDC7 (0.36) | PARP1CDC7ALOX5ALOX5APFEN1 | |
| SCHEMBL18198141 | 0.75 | PARP1 (0.38) | PARP1CDC7ALOX5ALOX5APFEN1 | |
| Hydrochloric Acid SCHEMBL18209674 | 0.73 | CDC7 (0.36) | PARP1CDC7ALOX5ALOX5APFEN1 | |
| SCHEMBL20400002 | 0.73 | CDC7 (0.33) | PARP1CDC7ALOX5ALOX5APFEN1 | |
| SCHEMBL18215199 | 0.71 | ALOX5 (0.41) | PARP1CDC7ALOX5ALOX5APFEN1 | |
| SCHEMBL27199355 | 0.70 | CYP1A2 (0.39) | PARP1CDC7ALOX5ALOX5APFEN1 | |
| SCHEMBL26988582 | 0.70 | ALOX5 (0.36) | PARP1PLATCDC7ALOX5ALOX5AP | |
| SCHEMBL16682636 | 0.69 | PARP1 (0.45) | PARP1PLATCDC7ALOX5ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749669-B3 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2024-09-04 | — | — | EP | claimed |
| EP-3749669-B1 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2023-03-08 | — | — | EP | claimed |