Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30363160 | 0.81 | CHRNA7 (0.67) | CHRNA7ADRA1DADRA1AADRA1BCYP2D6 | |
| SCHEMBL2887057 | 0.81 | CHRNA7 (0.67) | CHRNA7ADRA1DADRA1AADRA1BCYP2D6 | |
| SCHEMBL30363084 | 0.81 | CHRNA7 (0.67) | CHRNA7ADRA1DADRA1AADRA1BCYP2D6 | |
| Desbromoarborescidine A SCHEMBL31662855 | 0.78 | CHRNA7 (0.66) | CHRNA7ADRA1DADRA1AADRA1BCYP2D6 | |
| Desbromoarborescidine A SCHEMBL29002756 | 0.78 | CHRNA7 (0.66) | CHRNA7ADRA1DADRA1AADRA1BCYP2D6 | |
| Desbromoarborescidine A SCHEMBL5269957 | 0.78 | CHRNA7 (0.66) | CHRNA7ADRA1DADRA1AADRA1BCYP2D6 | |
| Desbromoarborescidine A SCHEMBL30363173 | 0.78 | CHRNA7 (0.66) | CHRNA7ADRA1DADRA1AADRA1BCYP2D6 | |
| SCHEMBL29458059 | 0.76 | CHRNA7 (0.64) | CHRNA7ADRA1DADRA1AADRA1BCYP2D6 | |
| SCHEMBL3859034 | 0.76 | CHRNA7 (0.64) | CHRNA7ADRA1DADRA1AADRA1BCYP2D6 | |
| SCHEMBL3868594 | 0.76 | CYP2D6 (0.53) | CHRNA7ADRA1DADRA1AADRA1BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113679731-B | Application of prunasin in preparation of medicine for treating fatty liver disease and hepatic fibrosis | 上海中医药大学附属曙光医院 | 2023-03-31 | — | — | CN | disclosed |